Vitamin D3 + K2 (MK-7)

Vitashine™ D3 from lichen · BioEssence™ MK-7 · Plant-based

D3 improves calcium absorption from your gut — but without K2, that calcium can deposit in arteries rather than bone. BioEssence MK-7 activates the proteins that direct calcium to where it belongs. Two nutrients. One capsule. Sourced from plants, not animals.

649.00

60 capsules · 60-day supply · ₹10.8 per day

Why it works

What D3 + K2 does that D3 alone cannot.

Vitamin D3 and K2 are partners, not alternatives. D3 absorbs calcium. K2 directs it. Without both, you’re only doing half the job — and potentially causing harm.
Immune System Regulation
Vitamin D3 is not just a vitamin — it functions as a steroid hormone that binds to receptors in almost every immune cell. D3 modulates both innate (first response) and adaptive (targeted) immunity. Deficiency is strongly associated with increased susceptibility to respiratory infections, autoimmune conditions, and systemic inflammation. With 76% of Indians estimated to be deficient, immune function is the most immediate benefit for most users.
Bone Strength & Density
D3 increases calcium absorption from food by 30–40%. But that calcium needs to reach bone, not arteries. K2 activates osteocalcin — the protein that binds calcium into bone matrix — and activates Matrix GLA Protein (MGP) which prevents calcium deposition in arterial walls. D3 without K2 can theoretically increase arterial calcification. Together, they build bone and protect arteries simultaneously.
Cardiovascular Protection
Arterial calcification (hardening of arteries) is a leading risk factor for heart disease. K2 MK-7 activates MGP, the body’s primary defence against arterial calcium deposits. Rotterdam Study data showed high K2 intake was associated with 57% lower risk of dying from heart disease and significant reduction in arterial calcification scores.
Muscle Strength
Vitamin D receptors are present in skeletal muscle tissue. D3 deficiency is associated with muscle weakness, slow reaction time, and increased fall risk in older adults. Studies show D3 supplementation improves grip strength, balance, and physical performance — particularly relevant for anyone who spends most of their day indoors and doesn’t get adequate sun exposure.
Mood & Mental Health
Vitamin D3 receptors are found throughout the brain, including regions involved in mood regulation. D3 is involved in serotonin synthesis — the neurotransmitter most associated with wellbeing and mood stability. Low D3 is consistently associated with depression symptoms. Supplementation in deficient individuals produces measurable improvements in mood scores.
Lung Health & Respiratory Function
D3 supports antimicrobial peptide production in lung tissue and modulates the inflammatory response in respiratory infections. Studies show D3-sufficient individuals have shorter, less severe respiratory illnesses. For urban Indians with high air pollution exposure and low sun exposure, maintaining adequate D3 levels is particularly important for respiratory health.

Full label transparency

Every ingredient declared. Every dose stated.

Supplement Facts

Serving: 1 Capsule · 60 Servings
Vitashine® Vitamin D3 (Cholecalciferol)
from lichen (Cladina arbuscula)             600 IU / 15mcg 100%
BioEssence® Vitamin K2 MK-7
fermentation-derived, long-acting                   55mcg
Microcrystalline Cellulose (MCC, INS 460)                   — —
%RDA as per ICMR 2020 guidelines for adults. ** No established RDA for Vitamin K2 (ICMR has RDA for K1 only); 55mcg MK-7 is an evidence-based dose from clinical research.

Why MCC? At 600 IU D3 + 55mcg K2, the active ingredient mass is very small. MCC provides the minimum fill volume needed for consistent capsule filling. We chose MCC over rice flour because rice flour degrades MK-7 potency during shelf life. We disclose this because you should know everything in your capsule.

600 IU
D3

Vitashine® Vitamin D3
From lichen · Vegan · 100% RDA
Vitashine is the only commercially available plant-derived D3 (cholecalciferol) — sourced from lichen (Cladina arbuscula), a symbiotic organism that naturally synthesises D3. Most D3 comes from lanolin (sheep’s wool), making it unsuitable for vegans. Vitashine provides identical chemical D3 to lanolin-derived D3, with full vegan certification. The 600 IU dose meets 100% of ICMR RDA.

55 mcg
MK-7

BioEssence® Vitamin K2 MK-7
Longest-acting K2 form · Carboxylates MGP + Osteocalcin
K2 exists in several forms (MK-4, MK-7, MK-9). MK-7 has the longest half-life in blood (~72 hours vs ~1–2 hours for MK-4), meaning once-daily dosing maintains consistent tissue K2 levels. MK-7 activates both osteocalcin (directs calcium to bone) and Matrix GLA Protein (prevents arterial calcification). BioEssence is a documented, quality-controlled MK-7 with batch-level traceability.

The research

The D3 deficiency epidemic in urban India.

76%

Proportion of urban Indians estimated to have insufficient Vitamin D levels (<20 ng/mL), despite India receiving abundant sunlight. The paradox is explained by modern indoor work culture, sun avoidance, high melanin in darker skin (reduces UV conversion efficiency), and air pollution blocking UV-B rays in Indian cities. Ritu G, Gupta A (2014). Vitamin D deficiency in India: prevalence, causalities and interventions. Nutrients.

57%

Reduction in cardiovascular mortality risk associated with higher Vitamin K2 intake, in the Rotterdam Study — a landmark 10-year population study. Participants in the highest K2 intake tertile also showed 52% lower rates of severe aortic calcification compared to those with lowest intake. K2 MK-7 form shows the strongest association. Geleijnse JM, et al. (2004). Dietary intake of menaquinone is associated with reduced risk of coronary heart disease. Journal of Nutrition.

72h

Half-life of MK-7 in blood circulation, compared to just 1–2 hours for MK-4. This pharmacokinetic advantage means once-daily dosing of MK-7 maintains active K2 levels throughout the 24-hour period, ensuring continuous carboxylation of osteocalcin and MGP. MK-4 requires multiple daily doses to achieve comparable tissue coverage. Schurgers LJ, et al. (2007). Vitamin K-containing dietary supplements. Blood.

+26%

Greater calcium absorption with adequate Vitamin D3 status compared to D3-deficient individuals. Without D3, calcium absorption from food drops to passive diffusion (~10–15%). With D3, active transport increases absorption to 30–40%. This makes D3 essential for anyone relying on dietary calcium for bone health, regardless of how much calcium they consume. Heaney RP, et al. (2003). Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. Journal of the American College of Nutrition.

How to use

Dosage, timing, and what to expect.

When to take it

Take 1 capsule daily with a meal containing fat — D3 and K2 are both fat-soluble vitamins that absorb significantly better in the presence of dietary fat. Breakfast with eggs or any meal with ghee, oil, or nuts works well. Consistent daily timing is more important than the specific meal.
How long until results

Blood vitamin D levels begin rising within 2–3 weeks. Noticeable immune improvements are often reported within 4–6 weeks. Bone density changes take months and require consistent long-term supplementation. Many people report improved energy and mood within the first month, particularly those who were significantly deficient.
Should I get my levels tested?

Ideally, yes. A 25(OH)D blood test costs ₹600–800 at most diagnostic labs. Target level: 40–60 ng/mL for optimal health. If your level is below 20 ng/mL, you may need a higher therapeutic dose (2000–5000 IU/day) to correct deficiency before switching to maintenance. Consult your doctor.

Important Note

People taking warfarin (blood thinner) should consult their doctor before adding K2, as K2 affects coagulation pathways. People with hypercalcemia (high blood calcium), hyperparathyroidism, or certain kidney conditions should consult a doctor before supplementing with D3. Very high D3 doses (>4000 IU/day) can cause vitamin D toxicity — this product’s 600 IU dose is safe for virtually all adults.

Frequently asked questions

Everything you want to know before you buy.

Why do I need K2 if I'm taking D3?
Vitamin D3 significantly increases calcium absorption from your gut — which is its intended function for bone health. But increased calcium in your blood needs to be directed to bone and teeth, not deposited in arteries, kidneys, or soft tissue. Vitamin K2 activates osteocalcin (which binds calcium into bone) and Matrix GLA Protein (which keeps calcium out of arteries). Without adequate K2, supplementing D3 alone may increase arterial calcification risk. The two nutrients are genuinely synergistic — each makes the other work better and safer.
Almost certainly yes. UV-B radiation — the specific wavelength that triggers D3 synthesis in skin — is blocked by air pollution, glass windows, clothing, and sunscreen. If you work indoors, commute by car or enclosed transport, and apply sunscreen, you receive negligible UV-B exposure regardless of how sunny the city is. Studies consistently show D3 deficiency in urban Indians across all Indian cities. The sun exposure needed for adequate D3 synthesis (direct midday sun, on significant skin area, without sunscreen, for 15–30 minutes) is simply incompatible with modern urban lifestyles.
Vitashine is the only commercially produced plant-derived Vitamin D3 (cholecalciferol). It’s sourced from lichen — a symbiotic organism that naturally photosynthesises D3 when exposed to UV light. This makes Vitashine chemically identical to the D3 produced by human skin in sunlight, but from a fully plant-based source. The alternative — what virtually all other D3 supplements use — is lanolin (the waxy secretion from sheep’s wool), making them non-vegetarian. Given India’s large vegetarian and Jain population, we chose Vitashine specifically.
Menaquinone-7 (MK-7) and Menaquinone-4 (MK-4) are both forms of Vitamin K2, but they have very different pharmacokinetics. MK-4 has a blood half-life of 1–2 hours, meaning it’s metabolised and excreted quickly. MK-7 has a half-life of approximately 72 hours, providing sustained activation of K2-dependent proteins throughout the day from a single dose. For once-daily supplementation, MK-7 is significantly more effective. Most research showing K2 cardiovascular benefits — including the Rotterdam Study — used MK-7.
Yes — and we recommend it. Magnesium is a required cofactor for the enzyme that converts Vitamin D3 into its active hormonal form (calcitriol). Without adequate magnesium, Vitamin D3 supplementation is less effective because the conversion step is impaired. Taking magnesium alongside D3 improves D3 bioactivity. This is one of the key reasons these three products (Omega-3, Magnesium, D3+K2) work well as a combined stack.

Learn more

From our research

Evidence-based articles — why form matters, how much you need, and what the science actually says.

MK-7 vs MK-4: The Vitamin K2 Form That Actually Lasts

Vitashine vs Lanolin D3: Why the Source of Your Vitamin D3 Matters

Can’t Sleep? Your Magnesium Levels Might Be Part of It

The Magnesium-Stress Cycle: What Causes It and How to Break It